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Susceptibility of Beavers to Chronic Wasting Disease

Chronic wasting disease is increasing across the landscape, and this is threatening other wildlife species in addition to cervids. Our objective was to evaluate the possibility that chronic wasting disease could transmit to beavers. Our results indicate that beavers are … read more

Examination of the interaction between age-specific predation and chronic disease in the Greater Yellowstone Ecosystem

The patterns of parasite infections in wildlife hosts often have an age component. For example, the prevalence of chronic infections tends to skew towards older individuals that have had a longer amount of time to be exposed (e.g. Heisey et … read more

The Role of Wolves in Regulating a Chronic Non-communicable Disease, Osteoarthritis, in Prey Populations

It is widely accepted that predators disproportionately prey on individuals that are old, weak, diseased or injured. By selectively removing individuals with diseases, predators may play an important role in regulating the overall health of prey populations. However, that idea … read more

Reduction of Chronic Wasting Disease Prion Seeding Activity following Digestion by Mountain Lions

Chronic wasting disease (CWD) is a transmissible prion disease first observed in the 1960s in North America. This invariably fatal disease affects multiple cervid species in the wild and in captivity. In addition to the several known transmission pathways involving … read more

Dogs are resistant to prion infection, due to the presence of aspartic or glutamic acid at position 163 of their prion protein

Unlike other species, prion disease has never been described in dogs even though they were similarly exposed to the bovine spongiform encephalopathy (BSE) agent. This resistance prompted a thorough analysis of the canine PRNP gene and the presence of a … read more

Sarcoptic mange severity is associated with reduced genomic variation and evidence of selection in Yellowstone National Park wolves (Canis lupus)

Population genetic theory posits that molecular variation buffers against disease risk. Although this “monoculture effect” is well supported in agricultural settings, its applicability to wildlife populations remains in question. In the present study, we examined the genomics underlying individual-level disease … read more

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