Posts Tagged: canids
Dogs are resistant to prion infection, due to the presence of aspartic or glutamic acid at position 163 of their prion protein
December 30, 2021
Unlike other species, prion disease has never been described in dogs even though they were similarly exposed to the bovine spongiform encephalopathy (BSE) agent. This resistance prompted a thorough analysis of the canine PRNP gene and the presence of a … read more
Posted in CWD & Other Diseases | Tagged canids, canine, dog, interspecies transmission, prion infection, prion susceptibility, scrapie, transgenic mouse models, transmissible spongiform encephalopathy, transmission barrier
Unraveling the key to the resistance of canids to prion diseases
March 6, 2020
One of the characteristics of prions is their ability to infect some species but not others and prion resistant species have been of special interest because of their potential in deciphering the determinants for susceptibility. Previously, we developed different in … read more
Posted in CWD & Other Diseases | Tagged canids, disease, PLOS, Prion, Wolf, wolves
A Genome-wide Perspective On The Evolutionary History Of Enigmatic Wolf-like Canids
June 30, 2019
High-throughput genotyping technologies developed for model species can potentially increase the resolution of demographic history and ancestry in wild relatives. We use a SNP genotyping microarray developed for the domestic dog to assay variation in over 48K loci in wolf-like … read more
Posted in Genetics | Tagged canids, enigmatic, evolutionary, genome, history, perspective
A Genome-wide Perspective On The Evolutionary History Of Enigmatic Wolf-like Canids
June 28, 2019
High-throughput genotyping technologies developed for model species can potentially increase the resolution of demographic history and ancestry in wild relatives. We use a SNP genotyping microarray developed for the domestic dog to assay variation in over 48K loci in wolf-like … read more
Posted in Coywolf / Hybrids | Tagged canids, enigmatic, evolutionary, genome, history, perspective
